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Who Shows Signs of Coronavirus

Who shows evidence of past SARS-CoV-2 infection? An interesting article by Silvia Stringhini and others published in The Lancet June 2020 assessed the burden of COVID-19 within a population of Geneva.  They found that children between the age of 5 and 9 and those...

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Dexamethasone and COVID-19

Advance in Treatment as Confirmed by Boris Johnson for COVID-19 Infection Last Week Dexamethasone This is a cheap, accessible steroid which has been available for many years.  The real breakthrough was that the recovery trial undertaken by the University of...

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COVID-19 World Population Risk

How much of the World’s population is at an increased risk of severe COVID-19 disease? A study published by Andrew Clark and others in The Lancet tried to answer this question. The risk of severe COVID-19 disease is known to be higher in older individuals and those...

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How does Coronavirus enter the body?

How does the SARS-CoV-2 virus enter the human body? Ludovico Cantuti-Castelvetri and others have identified a new possible pathway through which the SARS-CoV-2 enters into the central nervous system.  SARS-CoV-2 uses angiotensin-converting enzyme 2 as a host...

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How is COVID-19 Spread

What is the dominant route for the spread of Covid-19? Zhang and others published a research article in the Proceedings of the National Academy of Sciences of the United States of America, PNAS.  They analysed the trend and mitigation measures in three epicentres...

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COVID-19 What is the Culprit

What is the Culprit in the COVID-19 Disease? The Lancet Infectious Disease Journal highlights a comment by Yi and others, which helps to identify a possible route for transmission of the SARS-CoV-2 virus into the human and its resultant effect.  The COVID-19...

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Coronavirus and Cholesterol

Does high cholesterol lead to more severe COVID-19 infection? An abstract by Hao Wang & others revealed that when they loaded cells with cholesterol from blood serum using transport in apolipoprotein E this enhanced the endocytic entry of SARS-CoV-2.  High...

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COVID-19 the next step?

Asymptomatic SARS-CoV-2 Infection: What is the next step after lockdown? An important challenge for returning to normality is the prevalence of asymptomatic infection and the question of whether such individuals could sustain community virus transmission.  Two...

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Why have death rates from Coronavirus plateaued

Why have deaths from COVID-19 plateaued in Europe? Is this due to herd immunity? Transmission of SARS-CoV-2 appears to be in marked decline in many countries in Europe, North America and parts of Asia.  This follows unprecedented governmental interventions, which...

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Social Distancing and COVID-19

Physical distancing, face masks and eye protection, do they prevent person-to-person transmission of SARS-CoV-2 and COVID-19? A review published in The Lancet by Derek Chu and others June 1, 2020. The authors aimed to investigate the effects of physical distance, face...

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