TruAge & TruHealth FAQs
At The London General Practice (LGP), we believe that living longer isn’t just about adding years to your life – it’s about making those years healthier and better.
What’s the difference between biological age and chronological age
Chronological age is the actual number of years you’ve been alive. Biological age represents how old your cells and tissues truly are, reflecting your overall health, lifestyle, and environment. While chronological age is fixed, biological age can change depending on lifestyle choices and health status
What’s the difference between epigenetics and genetics?
TruAge & TruHealth Combo
At LGP, we use the most advanced biological age testing with system-level health analysis to deliver a full-spectrum view of both aging and cellular health across 185+ epigenetic biomarkers, all from one convenient test.
What differentiates TruDiagnostic from it’s competitors?
TruDiagnostic offers:
- Most Validated: Peer-reviewed algorithms developed with Harvard, Yale, and Columbia
- Most Precise & Accurate: Uses the largest database for DNA methylation, ensuring robust analysis
- Most Actionable: Measures your speed of aging, allowing personalized lifestyle adjustments to improve health.
The TruAge test evaluates biological age and organ health, while the TruHealth test assesses nutritional biomarkers to optimize dietary and lifestyle interventions
Is telomere length an accurate representation of aging?
Does the TruDiagnostic test measure COMT/MTHFR genes?
No. TruDiagnostic tests measure DNA methylation patterns affecting gene expression, not specific genetic mutations like COMT or MTHFR.
Are TruDiagnostic tests considered genotyping tests?
No. TruDiagnostic tests are epigenetic tests that measure changes in DNA methylation patterns affecting gene activity. Genotyping tests examine static genetic sequences.
What’s the difference between DNA methylation (DNAm) analysis and genotyping?
DNA methylation analysis assesses how your genes are expressed, influenced by lifestyle and environment. Genotyping identifies fixed genetic variants that remain unchanged throughout your life.
What is the turnaround time (TAT) for receiving results?
You ll typically receive results within 2 3 weeks after your sample arrives at our lab.
What are Epigenetic Biomarkers (EBs)?
EBs are predictive tools developed from DNA methylation data to serve as surrogates for clinical lab tests, metabolomic, and proteomic measurements. They provide disease risk predictions and diagnostic insights with a single blood sample of a few drops of blood
How do EBs compare to traditional biomarkers?
On average, clinical EBPs outperform traditional lab-based biomarkers in both prediction and diagnosis
- 62% of EBs provide stronger associations with the development of diseases
- 64% of EBs offer increased diagnostic disease associations.
As shown in our publication with Harvard “Leveraging DNS methylation to create Epigenetic Biomarker Proxies that inform clinical care: A new framework for Precision Medicine”.
What diseases can EBs predict or diagnose?
EB Risk Scores have been validated across a variety of chronic diseases, including:
- Cardiovascular disease
- Chronic Kidney Disease
- Cognitive Decline
- Chronic Liver Disease
- Type 2 Diabetes
How accurate are EBs?
EBs demonstrated:
- 90% overall accuracy in detecting deviations from clinical norms
- High overall specificity (94%) and sensitivity (76%) across clinical labs
What makes EBs revolutionary for healthcare?
- Non invasive and cost effective: Blood spot collection via finger prick replaces expensive and invasive procedures
- Broad coverage: Over 1,600 EBs assess multiple health parameters simultaneously
- Personalized insights: Enables targeted recommendations for disease prevention and management.
How were clinical EBs validated?
- Over 30,000 individuals from diverse health backgrounds participated in studies
- Clinical EBs were tested for their ability to match or exceed traditional lab based measures across clinical and research datasets
How can EBs benefit underserved populations?
EBs require minimal infrastructure, making them ideal for remote areas or low resource settings. They align seamlessly with current healthcare systems, offering actionable insights at a fraction of the cost of traditional tests.